# SIMdrom Changelog
## development
### simdrom-cli
* Adapt API to new simdrom-core
* Introduce a seed option
* -- name to set a sample-name (overwrites name "Sampled" in vcf file)
* -bGC or -mGC
* het/hom/hemi support
### simdrom-core
* Two bugfixes in spike-in
* Mutation was not inserted if the variant was the last in a contig
* Error when two or mutations where inserted at the end of a contig
* big restructuring (using Builders, optionals, etc.)
* Fixing bug in ClinVarFilter (wrong object was used to write down the omim IDs)
* Fixing bugs in VCFSampler and SpikeIn
* Fixing seed option bugs (Collection.shuffle was still random even if a seed was set)
* Limiting possible alleles to max. 2. Something like 2/3/4 should not be possible anymore!
* fix in hardy weinberg
* add possibility to use hom/het/hemi allele counts from exac etc.
* Adding sex to simdrom
* user can define the sex of the simulated individual. It can be also be randomly assigned or it can be none (only autosomes)
* Hardy weinberg sampling works dependend on the sex on X and Y
* Same for ac hom/get/hemi
* generate genotype not correctly (consider all possible genotype, not only 2, seen at the side when using )
* adding gnomAD support using the genotype counts (GC) flag
* htsjdk 2.11.0
* update ClinVarFilter to support CLNREFSTAT
### manual
* creating readthedocs manual!
## v0.2
* no changelog available